Vision & Mission

REM Therapeutic Delivery Innovation Initiative
There is an emerging trend in drug delivery systems due to inherent limitations of conventional oral drug delivery systems, such as biopharmaceutical solubility and intestinal permeability. A solution to resolve this potential challenge is to develop translational drug delivery systems that are capable of targeted delivery of therapeutic agents and controlled drug release in a non-invasive manner.  
 
Market data suggest, pharmaceutical innovation is the driving force in the shift from conventional drugs, to a translational delivery system. Novel systems, capable of delivering drugs in therapeutic concentration to the target site in a controlled manner for enhanced efficacy with less side effects, have opened a new direction in spurring innovative activity. 
 
To test therapeutic alternatives of conventional methods, our consortium of University and Research Institutions will work to develop less-invasive or non-invasive routes for delivery systems that affect clinical outcomes in different disease conditions. Research will be focused on the following means to better understand translational drug delivery: 
 
Designing and developing novel drug delivery systems, such as devices for drug delivery and drug/device combination products and image-guided drug therapy
Preclinical and clinical data related to drug delivery systems using big data tool and omics approaches
Improving drug distribution, pharmacokinetics, clearance, with drug delivery systems compared to traditional dosing
Short-term and long-term biocompatibility of drug delivery systems and host responses
Biomaterials with growth factors for stem-cell differentiation in regenerative medicine and tissue engineering
 
REM’s vision:
Accelerate therapeutic delivery innovation and translation to treat disease. REM’s initiative will achieve this goal, which will position Georgia as a leading innovation hub in this intellectual space and benefit Georgia’s knowledge economy, by fostering interdisciplinary and multi-institutional collaborations and supporting research ranging from fundamental to translational to positively impact human health.
 
Opportunities for institution involvement:
Synergy grants to support investigators planning multi-institutional grants 
Annual retreat to bring investigators together from the three participating institutions
Workshops to highlight new technologies and model systems available across institutions
 
Existing Centers at Emory that could help support this initiative:
Emory Chemical Biology Discovery Center 
Emory Vaccine Center 
 
Existing Centers at UGA that could help support this initiative:
Complex Carbohydrate Research Center 
Center for Drug Discovery 
Center for Molecular Medicine 
Regenerative Bioscience Center (RBC)
Nanoscale Science and Engineering Center (NanoSEC) 
Center for Vaccines and Immunology 
 
Existing Centers at GA Tech that could help support this initiative:
Center for Immunoengineering
Center for Drug Design Development and Delivery
Center for Cell Manufacturing Technologies/Marcus Center for Therapeutic Cell Manufacturing and Characterization 
The Center for Pharmaceutical Development (CPD)
Integrated Cancer Research Center (ICRC)
Faculty associated with the computational biology and bioinformatics interdisciplinary graduate program